Obscure question about Kindle Profiles

Okay, so this might be a little confusing. I'm trying to set up two different profiles on my kindle fire, one for me and one for my wife. I've got them mostly set up and we can access each other's amazon libraries. So here's my question. Is there a way to use Calibre to send books to the kindle between the two profiles? Like if I want to put a book on my wife's profile, but not mine.