Blank pages in Epub when it is read.

I am just wondering if anyone has some words of wisdom about the blank pages issue in Epub readers? Is there anything in the code of the Epub you can add to prevent this phenomenon? It seems random on different Ereaders. No matter how clean the code is at the end of the section the blank page still appears when it is read with an Ereader. Thanks, Mattfr:help: